Updates on Diagnosis, Clinical Presentation, and Management of Ocular Cicatricial Pemphigoid (OCP): A Systematic Review

Authors

  • Hyder Osman Mirghani Prof. of Internal Medicine and Endocrine, Department of Internal Medicine, Faculty of Medicine, University of Tabuk, KSA. https://orcid.org/0000-0002-5817-6194
  • Aedah Alqrid Medical intern, Faculty of Medicine in Tabuk University, Tabuk, KSA.
  • Hadeel Albalawi Student, Faculty of Medicine in Tabuk University, Tabuk, KSA.
  • Saud Alshabab College of medicine, king khalid university, Abha, KSA. https://orcid.org/0009-0008-7087-253X
  • Dana Aljezany Student, Faculty of Medicine in Tabuk University, Tabuk, KSA.
  • Hamdan Alghamdi Student, Faculty of Medicine in Tabuk University, Tabuk, KSA.
  • Khalid Aljohani Student, Faculty of Medicine in Tabuk University, Tabuk, KSA.
  • Mohammed Almousa College of medicine, king khalid university, Abha, KSA. https://orcid.org/0009-0004-7460-5923
  • Ali Alshehri College of medicine, king khalid university, Abha, KSA.
  • Zeyad Alahmri College of pharmacy, King Khalid University, Abha, KSA. https://orcid.org/0009-0001-6439-5350
  • Sara Alsaidalani Student, Faculty of Medicine in king Abdulaziz University, Rabigh, KSA. https://orcid.org/0009-0008-2567-1501
  • Abdullah Alshahrani College of medicine, king khalid university, Abha, KSA.
  • Salman Alshamrani Student, Faculty of Medicine in Tabuk University, Tabuk, KSA.

DOI:

https://doi.org/10.54293/smhj.v4i2.106

Keywords:

Keywords: Ocular cicatricial pemphigoid; Diagnosis; Management; Systematic review.

Abstract

This study systematically searched literature on the diagnosis, clinical presentation, and management of ocular chronic pain (OCP), including eight studies with 168 patients. The most reliable method of diagnosis was biopsy, with inflammatory markers detected in a small proportion of patients. Some patients had systemic or oral involvement and associated Sjogren's syndrome. Common immune-suppressives were MFF and steroids. Cyclophosphamide is a good choice in severe cases. Methotrexate and Rituximab were used as a maintenance therapy. OCP is characterized by ocular involvement that progresses to fibrosis and scarring. Diagnostic hurdles and inconclusive results make a comprehensive examination and clinical suspicion crucial.

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Published

2024-04-27

How to Cite

1.
Osman Mirghani H, Alqrid A, Albalawi H, Alshabab S, Aljezany D, Alghamdi H, Aljohani K, Almousa M, Alshehri A, Alahmri Z, Alsaidalani S, Alshahrani A, Alshamrani S. Updates on Diagnosis, Clinical Presentation, and Management of Ocular Cicatricial Pemphigoid (OCP): A Systematic Review. SMHJ [Internet]. 2024 Apr. 27 [cited 2024 Jul. 23];4(2):89-96. Available from: https://www.smh-j.com/smhj/article/view/106

Issue

Section

Review Article